The IgA level is examined when diagnosing autoimmune diseases, such as rheumatoid arthritis, lupus, and celiac disease.
Immunoglobulins are proteins that function as antibodies, whose molecule consists of two heavy chains and two light chains. They are divided into groups based on the structure of the heavy chains: IgA, IgD, IgE, IgG, and IgM.
Immunoglobulin A (IgA) is an antibody that plays a central role in the immune function of mucous membranes. It works especially in the digestive tract and respiratory system.
Immunoglobulin A attaches to microbes on the surfaces of mucous membranes and prevents their attachment to the cell. In the blood, it protects the body from viruses, bacteria, and fungi, although less effectively than the most common human antibody, immunoglobulin G.
Immunoglobulin A also has a role in allergic reactions.
The IgA test can help doctors diagnose problems related to the immune system, intestines, liver, kidneys, and bone marrow. Individuals with a congenitally low IgA level or IgA deficiency have an increased risk of autoimmune diseases, infections, asthma, and allergies.
Immunoglobulin A levels are examined with a blood test.
Through Puhti, a celiac disease test package is available, which includes the IgA test. All Puhti tests can be ordered without a doctor’s referral. You can separately order a doctor’s remote consultation easily directly from the end of the result report if you want to discuss your results and health, if the results deviate from reference values, if you have symptoms, or if there is suspicion of disease.
Reference values for immunoglobulin A in adults:
Reference values may vary depending on the laboratory and the method of analysis. Puhti’s samples are taken and analyzed in Mehiläinen’s laboratories.
The celiac disease test includes the following examinations: tissue transglutaminase IgA antibodies (S -tTGAbA) and immunoglobulin A (Ig A). For a reliable celiac disease diagnosis, it is required that the person being tested has been on a gluten-containing diet for at least 6 weeks before the sample is taken.
Immunoglobulin A (IgA) is an antibody that plays a central role in the immune function of mucous membranes.
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Article updated:
25 April 2025